A study to assess the levels of two antibiotics in the blood when given together and separately

Study identifier:D4280C00011

ClinicalTrials.gov identifier:NCT01430910

EudraCT identifier:N/A

CTIS identifier:N/A

Study Complete

Official Title

A Phase I, 2-Part, Open-Label, Pharmacokinetic and Drug-Drug Interaction Study of CAZ104 (Avibactam and Ceftazidime in Healthy Subjects)

Medical condition

Healthy

Phase

Phase 1

Healthy volunteers

Yes

Study drug

CAZ104, Avibactam, Ceftazidime

Sex

All

Actual Enrollment

43

Study type

Interventional

Age

18 Years - 50 Years

Date

Study Start Date: 01 Sept 2011
Primary Completion Date: 01 Oct 2012
Study Completion Date: 01 Oct 2012

Study design

Allocation: Randomized
Endpoint Classification: Pharmacokinetics Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Basic Science

Verification:

Verified 01 Apr 2016 by AstraZeneca

Sponsors

AstraZeneca

Collaborators

-

Inclusion and exclusion criteria