The clinical significance of minimal change in reflux esophagitis based on the Gastroesophageal Reflux Disease Questionnaire - MIGHT

Exclusion Criteria

• - Patients who had shown the mucosal break or barrett esophagus at gastric
• mucosal barrier or lower oesophagus in endoscopic findings
• - Patient with a diagnosis of gastroesophageal reflux disease and who have
• received medication treatment
• - Patient who had received H2-receptor antagonists, prostaglandin, PPI,
• NSAIDs or aspirin, high dose steroid and anticoagulants for at least 5
• consecutive days in the 4-week period immediately preceding the diagnostic
• endoscopy
• - Patients with a history of operation due to gastrointestinal disease,
• malignancy, alcoholism, pregnancy (in female), breast feeding (in female)
• or systemic disease